Facile and efficient synthesis of magnetic fluorescent nanocomposites based on carbon nanotubes |
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| Affiliation: | 1. Medical Oncology Service, Hospital del Mar, IMIM (Hospital del Mar Research Institute), Pompeu Fabra University, Barcelona, Spain;2. Medical Oncology Service, Hospital 12 de Octubre, Madrid, Spain;3. Haematology and Medical Oncology Service, Hospital Clínico de Valencia, Valencia, Spain;4. Medical Oncology Service, Hospital Clínic de Barcelona, Barcelona, Spain;5. Medical Oncology Service, Hospital Universitario de Salamanca, Salamanca, Spain;1. School of Physical Science and Technology, Southwest University, Chongqing 400715, PR China;2. School of Mechanical and Control Engineering, Beijing Jiaotong University, Beijing 100044, PR China;1. Polymer Research Laboratory, Department of Organic and Biochemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran;2. Research Center for Pharmaceutical Nanotechnology (RCPN), Tabriz University of Medical Science, Tabriz, Iran;1. School of Materials Science and Engineering, Wuhan Textile University, Wuhan 430200, China;2. School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, China |
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| Abstract: | Multifunctional nanomaterials composed of magnetic and fluorescent nanoparticles have been one of the most extensive pursuits because of the potential application in bio-research. In this paper, we demonstrated an efficient method by coupling CdSe/CdS/ZnS quantum dots (QDs) with Fe3O4 magnetic nanoparticles(MNPs) while functionalized multiwall carbon nanotubes (f-MWCNTs) were used as matrix to synthesize a kind of magnetic fluorescent nanocomposite. Compared with other matrix materials, carbon nanotubes have the advantages of high surface areas and good biocompatibility. The incorporation of f-MWCNTs supplies plenty of nucleation sites for the preferential growth of Fe3O4 nanoparticles, avoiding the agglomeration phenomenon of Fe3O4 MNPs in traditional co-precipitation method. Moreover, the un-reacted functional groups of f-MCNTs can further adsorb biological species and drugs, averting the decline of fluorescent intensity caused by the modification of biological species and drugs. The synthetic product maintains the unique properties of rapid magnetic response and efficient fluorescence, which shows a broad application prospect in fluorescent labeling, biological imaging, cell tracking and drug delivery. |
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| Keywords: | Nanocomposites Fluorescence Magnetic Carbon nanotubes |
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