An Efficient Magnetic Heterogeneous Nanocatalyst for the Synthesis of Pyrazinoporphyrazine Macrocycles

ABSTRACT

In this study, a one-pot synthesis of metallopyrazinoporphyrazines starting from simple and readily available precursors including 2,3-diaminomaleonitrile, 1,2-dicarbonyl compounds, metal salts such as CuCl₂, CoCl₂, FeCl₂, and ZnCl₂ and urea in the presence of nano-Fe₃O₄ anchored sulfuric acid as an efficient superparamagnetic heterogeneous nanocatalyst was described. The particle size of the nanocatalyst was studied by scanning electron microscopy images and chemical information about its surface functionalization was confirmed by energy-dispersive X-ray spectroscopy spectra. This new multicomponent protocol includes some important aspects such as easy work-up procedure, high atom economy, and simple and green reaction conditions for the synthesis of a new class of porphyrazine derivatives carrying six-membered pyrazine rings annulated at the periphery of the tetrapyrrolic macrocycle.