Crown ether complex cation ionic liquids: synthesis and catalytic applications for the synthesis of tetrahydro-4H-chromene and 1,4-dihydropyridine derivatives |
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Authors: | Mehdi Abaszadeh Mohammad Seifi |
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Affiliation: | 1. Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran;2. Department of Chemistry, Faculty of Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Esfahan, Iran |
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Abstract: | A series of crown ether complex cation ionic liquids (CECILs) are synthesized by crown ethers chelated with sodium benzenesulfonates, and used as a green and environmental catalyst, for the synthesis of tetrahydro-4H-chromene and 1,4-dihydropyridine derivatives by three-component reactions of aromatic aldehydes and malononitrile with cyclic β-dicarbonyls or cyclic β-enaminoketones respectively, in H2O/EtOH (1:1), at the reflux condition. CECILs, as a green and environmental catalyst, can be easily obtained and are stable. Furthermore, high conversions, short reaction times, and cleaner reaction profiles are some of the advantages of this method. |
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Keywords: | Crown ether complex cation ionic liquids crown ethers sodium benzenesulfonates tetrahydro-4H-chromene 1 4-dihydropyridine |
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