柔性表面增强拉曼散射基底分析检测农残进展

表面增强拉曼光谱(SERS)是基于探针分子的指纹信息(分子振动、转动信息等),可应用于具有灵敏度和特异性分子结构研究的分析技术.SERS借助具有优异的等离子体性能的贵金属纳米材料作为基底,可对单组分或复杂多组分的痕量农药残留物进行分析检测.其中,柔性SERS基底具有孔隙率高、制备成本低、柔韧可折叠弯曲等特点,在复杂样品体系中提取、过滤、浓缩探针分子等应用中具有刚性SERS基底不可比拟的优势.柔性SERS基底主要是由基于生物基材料、聚合物和碳材料的3类材料来支撑和固定修饰表面提供光谱增强作用的贵金属纳米材料.重点综述了这3种类型的柔性SERS基底常用制备方法及应用,充分利用SERS的"指纹图谱"分析优势,介绍了柔性SERS基底应用于不同农药残留的最新研究进展.最后,对SERS技术发展和应用提出了亟待解决的问题.

Progress in detection of pesticide residues by flexible surface enhanced Raman scattering substrate analysis

Pesticides are used to inhibit fungi, prevent insect pests and regulate plant growth mechanism. the analysis of pesticide residues is of great significance to promote the sustainable development of agricultural products. Surface-enhanced Raman spectroscopy (SERS) has the advantages of non-invasion, high sensitivity and fingerprint recognition. Using precious metal nanomaterials with excellent plasma properties as the substrate, single-component or complex multi-component trace pesticide residues can be analyzed and detected. However, this kind of nanoparticles with high surface energy are easy to agglomerate, in order to solve this problem, researchers at home and abroad have proposed to introduce cellulose, polymers and carbon materials with large voids to support and fix the surface modified precious metal nanomaterials to provide spectral enhancement. In this paper, the common preparation methods and applications of different types of flexible SERS substrates (cellulose, transparent tape, polymers, biomass materials, carbon materials, etc.) were reviewed, and the latest research progress in the application of flexible SERS substrates to different pesticide residues was introduced by making full use of the advantages of SERS fingerprint analysis. Finally, the problems to be solved urgently for the development and application of SERS technology are put forward.