Suppressive effects of interleukin-10 on human mononuclear phagocyte function against Candida albicans and Staphylococcus aureus |
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| Authors: | E Roilides A Anastasiou-Katsiardani A Dimitriadou-Georgiadou I Kadiltsoglou S Tsaparidou C Panteliadis TJ Walsh |
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| Affiliation: | 3rd Department of Pediatrics, University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece. |
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| Abstract: | ![]()
The effects of interleukin (IL)-10, a potent antiinflammatory cytokine, on human monocyte functions against two medically important pathogens, Candida albicans and Staphylococcus aureus, were studied. Incubation with 20-100 ng/mL IL-10 for 2-3 days decreased the fungicidal activity of monocytes against serum-opsonized C. albicans blastoconidia (P
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