| 金橘咀嚼片配方工艺 |
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| 引用本文： | 黄华花,张萌,王明军,王圣江,吕诗诗,陈缘缘.金橘咀嚼片配方工艺[J].食品工业,2020(4):142-146. |
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| 作者姓名： | 黄华花 张萌 王明军 王圣江 吕诗诗 陈缘缘 |
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| 作者单位： | 福建省中药精加工与健康产品开发重点研究室/厦门市中药生物工程重点实验室 |
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| 基金项目： | 福建省中医药重点研究室项目(No.ZD201405);福建省教育厅中青年教育科研项目(JT180659);院大学生创新创业训练计划项目(201812631050)。 |
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| 摘 要： | 以金橘为主要原料,采用湿法制粒压片工艺,以颗粒产率、片重差异、硬度、脆碎度、口感及感官评价的综合评分为评价指标,通过响应面法对金橘咀嚼片配方进行优化。结果表明,响应面法优化的金橘咀嚼片配方工艺为:金橘70%,山梨醇15%,微晶纤维素15%,以60%乙醇为润湿剂,硬脂酸镁量为干颗粒重的0.50%。在此条件下金橘咀嚼片的综合评分为1.1026。所优化的配方工艺稳定可行,可为金橘咀嚼片的规模化生产提供参考。
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| 关 键 词： | 金橘 咀嚼片 配方 响应面法 |
The Formulation of Fortunella margarita Chewable Tablets |
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| HUANG Huahua,ZHANG Meng,WANG Mingjun,WANG Shengjiang,Lü Shishi,CHEN Yuanyuan.The Formulation of Fortunella margarita Chewable Tablets[J].The Food Industry,2020(4):142-146. |
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| Authors: | HUANG Huahua ZHANG Meng WANG Mingjun WANG Shengjiang Lü Shishi CHEN Yuanyuan |
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| Affiliation: | (Key Laboratory of Traditional Chinese Medicine Finish Processing and Health Product Development of Fujian Province/Xiamen Key Laboratory of Traditional Chinese Medicine Bioengineering,Department of Pharmacy,Xiamen Medical College,Xiamen 361023) |
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| Abstract: | Using Fortunella margarita as the main raw material,Fortunella margarita chewable tablets were produced by wet granulation process.With the comprehensive score of particles yield,weight difference,hardness,brittleness,taste and sensory evaluation as evaluation index,the formulation was optimized by response surface methodology.The results showed that the optimized formulation of Fortunella margarita chewable tablets was as follows:the amount of Fortunella margarita powder of 70%,the amount of sorbitol of 15%,the amount of micro crystal cellulose(MCC)of 15%,and the amount of magnesium stearat of 0.50%,with 60%ethanol as the wetting agent.Under these conditions,the comprehensive score of Fortunella margarita chewable tablets was 1.1026.The optimized formulation was stable and feasible,which provided an important reference for large-scale production of Fortunella margarita chewable tablets. |
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| Keywords: | Fortunella margarita chewable tablets formulation response surface methodology |
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