The Synthesis of Vicinal Diacylamines via Bamberger Ring Cleavage of Substituted Imidazoles. 1,2,4-Triacylaminobutanes Bearing Different Acyl Groups |
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| Authors: | Janina Altman Nurit Shoef Meir Wilchek Abraham Warshawsky |
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| Affiliation: | 1. Department of Biophysics, The Weizmann Institute of Science, Rehovot, Israel;2. Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot, Israel |
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| Abstract: | Bamberger ring cleavage acylation of N-p-toluenesulfonyl (tosyl) histamine followed by hydrogenation yields 3,4-diacylaminobutanetosylamine, a triamine containing groups with different chemical reactivities. |
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