首页 | 本学科首页   官方微博 | 高级检索  
     


Diagnosis of sickle-cell disease by DNA analysis in Nigeria
Authors:TA Adewole  DK Olukoya  A Afonja
Affiliation:Nigerian Institute of Medical Research, Yaba-Lagos, Nigeria.
Abstract:
OBJECTIVE: To compare genotyping of leucocyte DNA by PCR and Dde I with the conventional genotyping of haemoglobin of the same subject. DESIGN: Comparative study. SUBJECTS: 25 adults, 16 males and nine females. MAIN OUTCOME MEASURES: Predictability. RESULTS: In all cases the results were comparable. CONCLUSIONS: The technology can be applied locally to prenatal diagnosis of sickle-cell disease by chorionic sampling and, therefore, improve the management of sickle-cell disease in Nigeria.
Keywords:
本文献已被 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号