Case reports of malformations associated with maternal diabetes: history and critique |
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| Authors: | H Kalter |
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| Affiliation: | Division of Basic Science Research, Children's Hospital Research Foundation, Cincinnati, OH 45229-2899. |
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| Abstract: | Several malformations and malformation complexes have been alleged to be associated with maternal type 1 diabetes mellitus: in particular, sacral dysplasia, caudal regression/sirenomelia, femoral dysplasia, and holoprosencephaly. For some of the malformations the claim rests on case material, and for others on theoretical considerations. The history and evolution of these ideas are presented. |
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