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壳聚糖/明胶复合微球的制备
引用本文:周佳男,周智华,孔令臣,孙少晨,郭立军,张金丽,黄荣艳,杨中民. 壳聚糖/明胶复合微球的制备[J]. 粉末冶金材料科学与工程, 2011, 16(5): 787-793
作者姓名:周佳男  周智华  孔令臣  孙少晨  郭立军  张金丽  黄荣艳  杨中民
作者单位:湖南科技大学理论化学与分子模拟教育部重点实验室,湘潭,411201
基金项目:湖南省科技厅计划资助项目(2010SK3060); 湖南省大学生研究性学习和创新性实验计划项目(湘教通[2010]244号); 国家自然科学基金资助项目(50604017)
摘    要:采用乳化-凝聚法,在油包水(W/O)体系中制备壳聚糖/明胶(Cs/Gel)复合微球,研究乳化剂用量、搅拌速率和水油比等因素对微球粒径以及脱水过程中的丙酮浓度对Cs/Gel复合微球形貌的影响.研究结果表明:乳化剂浓度较低时,微球的粒径随乳化剂浓度的增加呈降低趋势,当乳化剂浓度高于0.012 g·mL-1时微球粒径不再发生...

关 键 词:Cs/Gel复合微球  制备  粒径  形貌

Preparation of chitosan/gelatin composite microsphere
ZHOU Jia-nan,ZHOU Zhi-hua,KONG Ling-chen,SUN Shao-chen,GUO Li-jun,ZHANG Jin-li,HUANG Rong-yan,YANG Zhong-min. Preparation of chitosan/gelatin composite microsphere[J]. materials science and engineering of powder metallurgy, 2011, 16(5): 787-793
Authors:ZHOU Jia-nan  ZHOU Zhi-hua  KONG Ling-chen  SUN Shao-chen  GUO Li-jun  ZHANG Jin-li  HUANG Rong-yan  YANG Zhong-min
Affiliation:ZHOU Jia-nan,ZHOU Zhi-hua,KONG Ling-chen,SUN Shao-chen,GUO Li-jun,ZHANG Jin-li,HUANG Rong-yan,YANG Zhong-min (Key Laboratory of Theoretical Chemistry and Molecular Simulation,School of Chemistry and Chemical Engineering,Hunan University of Science and Technology,Xiangtan 411201,China)
Abstract:Chitosan/gelatin(Cs/Gel) composite microspheres were prepared through emulsion-coagulation method.The influences of preparation parameters,including emulsifier concentration,stirring speed and water/oil ratio,on microsphere's particle size and the concentration of acetone solution in the course of dehydration on the surface morphology were investigated.The research results indicate that the particle size of the microsphere decreases with increasing the concentration of the emulsifier;the particle size of th...
Keywords:Cs/Gel microspheres  preparation  particle size  morphology  
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