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基于三维限制区域生长的SD-OCT中浆NRD病变区域分割
引用本文:何晓俊,吴梦麟,范雯,袁松涛,陈强.基于三维限制区域生长的SD-OCT中浆NRD病变区域分割[J].计算机科学,2018,45(Z6):187-192, 219.
作者姓名:何晓俊  吴梦麟  范雯  袁松涛  陈强
作者单位:南京理工大学计算机科学与工程学院 南京210094,南京工业大学电子与信息工程学院 南京211816,南京医科大学第一附属医院江苏省人民医院眼科 南京210029,南京医科大学第一附属医院江苏省人民医院眼科 南京210029,南京理工大学计算机科学与工程学院 南京210094;闽江学院福建省信息处理与智能控制重点实验室 福州350121
基金项目:本文受国家自然科学基金面上项目(61671242),中央高校基本科研业务费专项资金(30920140111004),六大人才高峰(2014-SWYY-024),福建省信息处理与智能控制重点实验室(闽江学院)开放课题基金(MJUKF201706)资助
摘    要:中浆(CSC)病变区域的大小对于病变的诊断及研究有着关键的作用,而视网膜神经上皮层脱离(NRD)形态在中浆病变中最为普遍且病变程度最为严重,因此快速准确地分割出NRD病变区域十分重要。给出一种全自动的频域光学相干断层(SD-OCT)中浆NRD病变分割方法。首次在三维空间进行NRD病变分割,将二维图像上的病变区域分割问题转化为三维空间的体分割问题,充分利用了数据的三维结构信息,提高了分割精度。18组中浆NRD病变的SD-OCT图像的实验结果表明:该算法能够准确分割出中浆NRD病变,且平均覆盖率高达89.5%。与其他4种分割方法相比,所提方法精度最高且耗时最短,在临床应用与研究中具有极大的优势。

关 键 词:中心性浆液性脉络膜视网膜病变  视网膜神经上皮层分离  频域光学相干层析图像  自适应阈值  三维区域生长

SD-OCT CSC NRD Region Segmentation Based on Region Restricted 3D Region Growing
HE Xiao-jun,WU Meng-lin,FAN Wen,YUAN Song-tao and CHEN Qiang.SD-OCT CSC NRD Region Segmentation Based on Region Restricted 3D Region Growing[J].Computer Science,2018,45(Z6):187-192, 219.
Authors:HE Xiao-jun  WU Meng-lin  FAN Wen  YUAN Song-tao and CHEN Qiang
Affiliation:School of Computer Science and Engineering,Nanjing University of Science and Technology,Nanjing 210094,China,College of Electronics and Information Engineering,Nanjing University of Technology,Nanjing 211816,China,Dartment of Ophthalmology,The First Affiliated Hospital with Nanjing Medical University,Nanjing 210029,China,Dartment of Ophthalmology,The First Affiliated Hospital with Nanjing Medical University,Nanjing 210029,China and School of Computer Science and Engineering,Nanjing University of Science and Technology,Nanjing 210094,China;Fujian Provincial Key Laboratory of Information Processing and Intelligent Control,Minjiang University,Fuzhou 350121,China
Abstract:It is important to segment neurosensory retianl detachment (NRD) of central serous chorioretinopathy (CSC) region,because the volume of CSC region plays a very important role in the diagnosis and study of CSC,while NRD is the most common and serious situation in CSC.The paper presented an automated spatial-domain optical cohe-rence tomography (SD-OCT) NRD segmentation method,which firstly segments NRD lesion in 3D space.And the segmentation of lesion in two-dimensional images is transformed into three-dimensional space segmentation problem,which makes full use of the three-dimensional structure information of data and improves the segmentation precision.The experiment results with 18 SD-OCT cubes indicate that the proposed method can segment the NRD accurately,and the average area coverage is as high as 89.5%.Compared to other four segmentation methods,the proposed algorithm achieves the highest accuracy and costs the least time,which has great advantages in clinical application and research.
Keywords:Central serous chorioretinopathy  Neurosensory retianl detachment  Spatial-domain optical coherence tomography  Adaptive threshold  3-D region growing
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