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补肾延寿胶囊抗衰老作用
引用本文:陈金和,汪晖,丁虹,黎七雄,孔锐.补肾延寿胶囊抗衰老作用[J].金属学报,1999,4(1):30-32.
作者姓名:陈金和  汪晖  丁虹  黎七雄  孔锐
作者单位:湖北医科大学药理教研室,武汉 430071
摘    要:目的 观察补肾延寿胶囊对实验动物抗氧化功能、耐寒及抗疲劳功能的影响。方法 检测补肾延寿胶囊对老龄大鼠血红细胞超氧化物歧化酶(SOD)、组织丙二醛(MDA)含量以及阳虚症小鼠体重、体温和冰水游泳时间的影响。结果 补肾延寿胶囊(0.4、0.8g/kg ig,叫qd ×21日)既能升高老龄SD大鼠血红细胞SOD比活性,明显降低肝和脑组织MDA含量,也能增加氬化泼尼松所致阳虚症小鼠的体重、体温和冰水游泳时间。结论 结合补肾延寿股囊对免疫功能的增强和调节作用,提示补肾延寿胶囊具有一定的抗衰老作用。

关 键 词:补肾延寿胶囊  抗衰老  超氧化物歧化酶  丙二醛  阳虚症  
收稿时间:1998-12-21
修稿时间:1999-01-11

Antisenescent action of capsule bushenyanshou
CHEN Jin-He,WANG Hui,DING Hong,LI Qi-Xiong,KONG Rui.Antisenescent action of capsule bushenyanshou[J].Acta Metallurgica Sinica,1999,4(1):30-32.
Authors:CHEN Jin-He  WANG Hui  DING Hong  LI Qi-Xiong  KONG Rui
Affiliation:Deparlment of Phar macology, Hubei Medical University, WuHan 430071
Abstract:Aim The effect of capsule bushenyanshou (BSYS) on the antioxidative function, and the tolerance of cold and fatigue in rats was investigated. Methods The activity of erythro-cytic superoxide dismutase (SOD), the contents of brain and liver malondialdehyde (MDA) in rats and the changes of body weight, body temperature and the swimming time at (TC in mice were measured. Results Capsule BSYS(400, 800 mg/kg, ig, qd × 21d) increased erythrocytic SOD activity and markedly reduced brain and liver homogenate MDA contents in ole rat and enhanced ihe body weight and body temperature, and prolonged the swim-ming time at 0℃ in hydrocortisone-treated(15 mg/kg, sc, qd × 5 d) mice. Conclusion Capsule BSYS has a certain antisenescent action.
Keywords:capsule bushenyanshou  antisenescent action  erythrocytic superoxide dis-murase  malondialdehyde  hydrocortisone-treated mice  
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