| Effects of Er~（3＋） on the proliferation,differentiation and mineralization function of primary mouse osteoblasts in vitro |
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| 引用本文： | 张金超,孙静,张大威,李亚平,郝晓红,秦新英. Effects of Er~（3＋） on the proliferation,differentiation and mineralization function of primary mouse osteoblasts in vitro[J]. 中国稀土学报(英文版), 2011, 29(5): 507-510. DOI: 10.1016/S1002-0721(10)60487-5 |
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| 作者姓名： | 张金超 孙静 张大威 李亚平 郝晓红 秦新英 |
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| 作者单位： | Chemical Biology Key Laboratory of Hebei Province;College of Chemistry and Environmental Science;Hebei University;Affiliated Hospital of Hebei University;Department of Natural Product Chemistry;Shenyang Pharmaceutical University; |
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| 基金项目： | Project supported by the National Natural Science Foundation of China (20971034); Foundation for Key Program of Ministry of Education of China (208018); Returned Scholars of Hebei Province (207041); Nature Science Key Foundation of Hebei Province (B2009000161); Natural Science Foundation of Hebei University |
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| 摘 要： |
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| 关 键 词： | erbium ion osteoblasts proliferation differentiation mineralization rare earths |
| 收稿时间： | 2010-10-15 |
Effects of Er~(3+) on the proliferation,differentiation and mineralization function of primary mouse osteoblasts in vitro |
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| ZHANG Jinchao,SUN Jing ,ZHANG Dawei,LI Yaping ,HAO Xiaohong ,QIN Xinying. Effects of Er~(3+) on the proliferation,differentiation and mineralization function of primary mouse osteoblasts in vitro[J]. Journal of Rare Earths, 2011, 29(5): 507-510. DOI: 10.1016/S1002-0721(10)60487-5 |
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| Authors: | ZHANG Jinchao SUN Jing ZHANG Dawei LI Yaping HAO Xiaohong QIN Xinying |
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| Affiliation: | ZHANG Jinchao1,SUN Jing 2,ZHANG Dawei3,LI Yaping 1,HAO Xiaohong 1,QIN Xinying 1 (1. Chemical Biology Key Laboratory of Hebei Province,College of Chemistry and Environmental Science,Hebei University,Baoding 071002,China,2. Affiliated Hospital of Hebei University,Baoding 071000,3. Department of Natural Product Chemistry,Shenyang Pharmaceutical University,Shenyang 110016,China) |
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| Abstract: | A series of experimental methods including 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H tetrazolium bromide (MTT) test,alkaline phosphatase (ALP) activity measurement,oil red O stain and measurement,mineralized function and quantitive real time RT-PCR (qRT-PCR) were employed to assess the effects of Er3+ on the proliferation,differentiation and mineralization function of primary osteoblasts (OBs) in vitro at cell and molecular levels. The results indicated that Er3+ inhibited the proliferation of OBs at a c... |
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| Keywords: | erbium ion osteoblasts proliferation differentiation mineralization rare earths |
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