| 罗汉果内生真菌SG一69次级代谢产物的研究 |
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| 引用本文： | 陈海燕,付东兴,林翠梧,王志滨,覃江克.罗汉果内生真菌SG一69次级代谢产物的研究[J].陕西化工,2012(8):1318-1320. |
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| 作者姓名： | 陈海燕 付东兴 林翠梧 王志滨 覃江克 |
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| 作者单位： | [1]广西大学化学化工学院,广西南宁530004 [2]广西北航工程技术研究中心,广西南宁530022 [3]广西师范大学化学化工学院,广西桂林541004 |
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| 基金项目： | 国家自然科学基金（21102022）;广西自然科学基金（桂科自0728257）;广西师范大学药用资源化学及药物分子工程教育部重点实验室开放课题（桂科能07109001-15） |
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| 摘 要： | 罗汉果内生真菌SG-69的发酵培养液和菌体通过硅胶柱色谱、SephadexLH-20凝胶柱色谱和重结晶等方法分离，得到6个化合物，运用IR、。HNMR．13CNMR等波谱技术，结合化合物的理化性质、波谱数据与文献数据对照鉴定了其结构分别为麦角甾-5，7，22-三烯-3β一醇（1）、对羟基苯甲酸（2）、白僵菌酮（3）、苯乙酸（4）、尿囊素（5）和甘露醇（6），其中尿囊素（5）首次从罗汉果内生真菌中发现。研究结果表明，罗汉果内生真菌的次级代谢产物与宿主罗汉果化学成分有很大差异，有待进一步研究。
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| 关 键 词： | 罗汉果内生真菌 次级代谢产物 分离 鉴定 |
Study on the secondary metabolites of the endophytic fungus SG-69 from the Siraitia grosvenori |
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| CHEN ttai-yan,FU Dong-xing,LIN Cui-wu,WANG Zhi-bin,QIN Jiang-ke.Study on the secondary metabolites of the endophytic fungus SG-69 from the Siraitia grosvenori[J].Applied Chemical Industry,2012(8):1318-1320. |
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| Authors: | CHEN ttai-yan FU Dong-xing LIN Cui-wu WANG Zhi-bin QIN Jiang-ke |
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| Affiliation: | 1. College of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China; 2. Guangxi Institute of Engineering Technology, BUAA, Nanning 530022, China; 3. College of Chemistry and Chemical Engineering, Guangxi Normal University, Guilin 541004, China) |
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| Abstract: | The fermentation medium and the mycelium of the Siraitia grosvenori endophytic fungus SG-69 was extracted by ethyl acetate and methanol respectively. Six compounds were obtained by silica gel, Sephadex LH-20 column chromatography and recrystallization approaches. Using of IR,1H NMR, 13C NMR spectroscopy and the combination of compounds physicochemical properties and spectral data with literature data, their structures were identified as ergosterol （ 1 ） ,4-hydroxybenzoic acid （2）, bassiana ketone （ 3 ） , phenylacetic acid （4） , allantoin （ 5 ） , and mannitol （ 6 ）, respectively, in which compound （ 5 ） was first been isolated from the Siraitia grosvenori endophytic fungus. So the endophytic fungus secondary metabolites are different with the host Siraitia grosvenori chemical composition, it is worthy of further study Siraitia grosvenori endophytic fungus. |
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| Keywords: | Siraitia grosvenori endophytic fungus secondary metabolite isolation identification |
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