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PLGA nanodepots co-encapsulating prostratin and anti-CD25 enhance primary natural killer cell antiviral and antitumor function
Authors:Sweeney  Elizabeth E  Balakrishnan  Preethi B  Powell  Allison B  Bowen  Allan  Sarabia  Indra  Burga  Rachel A  Jones  R Brad  Bosque  Alberto  Cruz  C Russell Y  Fernandes  Rohan
Affiliation:The George Washington Cancer Center, The George Washington University, Washington, DC 20052, USA;Center for Cancer and Immunology Research, Children's National Health System, Washington, DC 20010, USA;Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, DC 20052, USA;Infectious Disease Division, Weill Cornell Medical College, New York, NY 10065, USA;The George Washington Cancer Center, The George Washington University, Washington, DC 20052, USA;Center for Cancer and Immunology Research, Children's National Health System, Washington, DC 20010, USA;The George Washington Cancer Center, The George Washington University, Washington, DC 20052, USA;Department of Medicine, The George Washington University, Washington, DC 20052, USA
Abstract:Nano Research - Natural killer (NK) cells are attractive effector cells of the innate immune system against human immunodeficiency virus (HIV) and cancer. However, NK cell therapies are limited by...
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