苄基三甲基碘化铵相转移催化合成N,N-二乙基苯胺的研究

使用苄基三甲基碘化铵作相转移催化剂可在常压下由苯胺和溴乙烷合成 N,N 二乙基苯胺 ,研究了反应时间 ,反应温度 ,催化剂用量 ,反应物摩尔比 ,氢氧化钠溶液浓度 ,氢氧化钠溶液用量等多种反应因素对目的产物产率的影响 ,提出了常压下催化合成目的产物的最佳工艺条件是 :在 50 m L,4 0 %的氢氧化钠溶液中 ,苯胺和溴乙烷的摩尔比为 1∶ 1 .75,苄基三甲碘化铵用量为 0 .75g,6 0℃下常压反应 4 h,产品产率 80 .4 %。

STUDY ON PHASE TRANSFER CATALYTIC SYNTHESIS OF N,NDIETHYLANILINE WITH TRIMETHYLBENZYLAMMONIUM IODIDE AS CATALYST

N,NDiethylaniline was synthesized from aniline and bromoethane with trimethyl benzylammonium iodide as phose transfer catalyst under normal atmosphere. The effect of the varied reaction factors such as reaction time reaction temephore the amount of catalyst, anilinebromoethane molar ratio, the concentration and amount of sodium hydroxide solution on yield of N,Ndiethylaniline has been studied. The optimum parameters for preparing N,Ndiethylanline have been proposed. The optimal reaction conditions were:anilinebromoethone molar ratio 1∶1.75 in 50 mL 40% sodium hydroxide solution. Catalyst 0.75 g reaction temephave 60 ℃, reaction time 4 h at under normal atmospher. The yield of N,Ndiethylaniline was 80.4%.