多模联振式超声波裂解系统的设计与优化

为了解决传统超声波裂解仪器裂解效率低、交叉污染风险高的问题,开发了多模联振式超声波裂解系统。通过仿真分析,发现球冠结构传振膜的前十阶振动模态的固有频率具有台阶式分布的规律,这为利用传振膜多阶模态的联合共振提供了可能。基于ANSYS模态分析,分别研究了曲率半径、厚度和预载力对传振膜多阶振动模态联合共振特性的影响,并对传振膜的结构参数和预载力进行了优化设计。据此加工制作传振膜,搭建多模联振式超声波裂解实验平台,并验证其裂解效能。生物实验结果显示,本文所设计的多模联振式超声波裂解系统的裂解率高于传统超声波裂解仪器。

Design and optimization analysis of ultrasonic lysis system basedon multi-mode synchronous resonance

To solve the defects of low lysis efficiency and high cross contamination risk in traditional contact ultrasonic lysis instrument, a ultrasonic lysis system based on multi-mode synchronous resonance is developed. Through finite element modal simulation analysis, it is found that the natural frequencies of the first ten order vibration modes of the diaphragm with dome-shaped structure have the ladder-like scattergram, which provides a possibility of utilizing the synchronous resonance of multiple order modes of the diaphragm. Based on ANSYS mode analysis, the effects of curvature radius, thickness and preload force on the synchronous resonance characteristics of multiple order modes of the diaphragm are studied, and then the structural parameters and the preload force of the diaphragm are optimized. Based on above, the diaphragm for vibration transmission was manufactured, the experiment platform of ultrasonic lysis system based on multi-mode synchronous resonance was established, and its lysis efficiency was evaluated. Biological experiment results prove that the lysis efficiency of the proposed ultrasonic lysis system based on multi-mode synchronous resonance is higher than that of traditional contact ultrasonic lysis instrument.