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| 母乳低聚糖与婴儿肠道菌群相关性研究进展 | |
| 引用本文： | 袁慧芝,荀一萍,蒲晓璐,朱宏,王世杰. 母乳低聚糖与婴儿肠道菌群相关性研究进展[J]. 食品科学, 2021, 42(13): 319-325. DOI: 10.7506/spkx1002-6630-20200605-072 |
| 作者姓名： | 袁慧芝 荀一萍 蒲晓璐 朱宏 王世杰 |
| 作者单位： | （1.河北科技大学食品与生物学院，河北 石家庄 050018；2.石家庄君乐宝乳业有限公司，河北 石家庄 050221） |
| 基金项目： | “十三五”国家重点研发计划重点专项（2018YFD0501606）；河北省省级科技项目重大专项（19027143Z）；河北省重点研发计划项目（19222812D）；石家庄市科学技术研究与发展计划项目（201170154A） |
| 摘 要： | 母乳中含有丰富的母乳低聚糖(human milk oligosaccharides HMOs),可以刺激新生儿肠道中有益细菌的生长从而起到益生元的作用.目前我国允许添加到婴幼儿配方奶粉中的低聚糖在结构上与HMOs不同,因此,它们无法模拟HMOs的某些结构特异性效应.本文综述了HMOs的组成、结构以及在母乳中的含量,重点... |
| 关 键 词： | 母乳低聚糖 组成结构 婴儿 肠道菌群 相关性 代谢产物 |
Progress in Understanding the Relationship between Human Milk Oligosaccharides and Infant Gut Microbiota |
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| YUAN Huizhi,XUN Yiping,PU Xiaolu,ZHU Hong,WANG Shijie. Progress in Understanding the Relationship between Human Milk Oligosaccharides and Infant Gut Microbiota[J]. Food Science, 2021, 42(13): 319-325. DOI: 10.7506/spkx1002-6630-20200605-072 | |
| Authors: | YUAN Huizhi XUN Yiping PU Xiaolu ZHU Hong WANG Shijie |
| Affiliation: | (1. College of Food Science and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China; 2. Shijiazhuang Junlebao Dairy Co., Ltd., Shijiazhuang 050221, China) |
| Abstract: | Breast milk is rich in human milk oligosaccharides (HMOs), which are prebiotics that can stimulate the growth of beneficial bacteria in the neonatal intestine. At present, the oligosaccharides allowed to be added to infant formula in China are structurally different from HMOs so that they cannot simulate some structure-specific effects of HMOs. This review describes the composition, structure and content of HMOs in breast milk, focusing on the relationship between HMOs as well as their metabolites and the infant intestinal microbiota. Finally, the beneficial effects of feeding infant formula with HMOs on the infant intestinal flora are discussed, which will provide theoretical support for promoting the application of HMOs in infant formula foods. |
| Keywords: | human milk oligosaccharides compositional structure infant gut microbiome correlation metabolites, |
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