| 核分析技术在基础医学研究中的若干应用 |
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| 引用本文： | 章净霞 姚惠英. 核分析技术在基础医学研究中的若干应用[J]. 核技术, 1994, 17(3): 158-163 |
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| 作者姓名： | 章净霞 姚惠英 |
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| 作者单位： | 北京医科大学，复旦大学，北京正负电子对撞机同步辐射实验室，中国科学院上海原子核研究所 |
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| 基金项目： | 北京正负电子对撞机国家实验室资助,上海核分析中心的资助 |
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| 摘 要： | 应用同步辐射Ｘ荧光微探针（ＳＲ－ＸＭＦ）和扫描质子微探针（ＳＰＭ）技术研究了基础医学领域中与微量元素有关的几个课题。初步实验结果表明，具有高灵敏度、高分辨率和对样品损伤小的ＳＲ－ＸＭＦ和ＳＰＭ技术特别适合于元素含量低的细胞和生物组织样品，这些技术是研究元素的细胞生理学，从细胞水平探讨微量元素的生物学作用机理以及从微观角度阐明疾病的致病机理等方面有独特作用的新手段。
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| 关 键 词： | 过氧化脂质 基础医学 微探针分析 |
Some applications of nuclear analytical techniques in basic medical science |
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| Zhang Jingxia, Huang Ping,Wu Benjie,Yu Guifen, Tian Hong,Zhang Xi, Xu Shiwen, An Lizhi. Some applications of nuclear analytical techniques in basic medical science[J]. Nuclear Techniques, 1994, 17(3): 158-163 |
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| Authors: | Zhang Jingxia Huang Ping Wu Benjie Yu Guifen Tian Hong Zhang Xi Xu Shiwen An Lizhi |
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| Abstract: | Some topics on trace elements in the field of basic medical science were studied by means of Scanning Proton Microprobe(SPM) and Synchrotron Radiation X-ray Fluorescence Microprobe(SR-XMF) techniques.The preliminary results indicate that these methods, with high sensitivity, high resolution and being non- destructive,are particularly fit for the basic medical science research. They are very useful tools in microscopic study of cellular physiology to probe the biological functions of trace elements and to demonstrate pathogenic mechanism of some diseases. |
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| Keywords: | Scanning Proton Microprobe(SPM) Synchrotron Radiation X-rayFluorescence Microprobe(SR-XMF) Lipoperoxidation |
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