Preparation and activity of a nanometer anti-microbial polyurethane

A novel way for photo-immobilization with interferon- α (IFN- α) on the surface of polyurethane (PU) material, which makes PU condom more effective function in the future, was investigated. A kind of photoactive arylazide-4-azidobenzoic acid was modified to IFN- α with the confirmation of IR and Raman spectrum. Micro morphology of the photo-immobilized cell factors was observed by FESEM as well as CSLM at the level of nanometer. Finally, the product with elementary test of anti-microbial was also evaluated. Funded by the Guangdong Technology Projects (No.2006B35802003), the Natural Science Foundation of Guangdong Province (No.8451063101000345) and the Opening Project of MOE Key laboratory of Laser Life Science, South China Normal University, Guangzhou 510631, China