The role of active oxygen radicals in blood system reactions in inflammation

On the model of carrageenan-induced acute aseptic peritonitis in rats with using of alpha-tocopherol it is shown that the active oxygen metabolites increase granulomonocytopoiesis, leukocytosis and stimulation of blood neutrophils, accumulation and activation of neutrophils of an inflammatory focus, decrease accumulation and stimulation of monocytes of an inflammatory focus and thus they are pro-inflammatory modulators of the blood system's reactions.