Profiles of daily secretion of ACTH, beta-endorphins and cortisol in patients after minor craniocerebral trauma

In 12 men aged 20-25 men who had minor craniocerebral trauma the profiles of daily secretion of ACTH, beta-endorphin and cortisol were studied. The studies were carried out on the second day after the trauma. Plasma concentrations of the hormones were determined on 8.00, 12.00, 17.00 and 22.00 hours. Statistically significantly increased, in relation to healthy persons, (p < 0.01) values of plasma hormone concentration were found at all time points. In 50% of the patients (six cases) a disturbance was found of the profile of daily secretion of ACTH and beta-endorphin. The disturbance of the profile of cortisol secretion was found only in one patient.