Pharmaceutical development and specification of stereoisomers |
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Authors: | RC Williams CM Riley KW Sigvardson J Fortunak P Ma EC Nicolas SE Unger DF Krahn SL Bremner |
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Affiliation: | Pharmaceutical Research and Development, DuPont Merck Pharmaceutical Company, Wilmington, DE 19880, USA. |
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Abstract: | ![]() The pharmaceutical development of chiral drugs requires the activities of many different research and development groups. Guidelines which help to coordinate the activities of these groups and assist in the successful development of compounds with either single or multiple chiral centers are outlined and discussed. |
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