| 2,5—二甲基—3,4—二乙酰基呋喃及其衍生物的合成 |
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| 引用本文： | 朱洪友,袁瑾.2,5—二甲基—3,4—二乙酰基呋喃及其衍生物的合成[J].云南化工,1997(2):28-29. |
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| 作者姓名： | 朱洪友 袁瑾 |
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| 作者单位： | 云南大学化学系 |
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| 摘 要： | 以ＫＩ－ＮａＩ为间接电解质，丙酮为溶剂，用间接电氧化的方法将乙酰丙酮（３）、乙酰乙酸乙酯（４）进行偶联反应，高产率地得到偶联产物四羰基化合物（５－６），进而在酸性介质中经Ｐａａｌ－Ｋｎｏｒｒ环化，合成了２，５－二甲基－３，４－二乙酰基呋喃（７）和２，５－二甲基－３，４－二乙氧羰基呋喃（８）。（７）再经ＮａＢＨ４还原得２，５－二甲基－３，４－二（１－羟基乙基）呋喃（９）。
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| 关 键 词： | 间接电氧化 多取代呋喃 偶联 KI－NaI／丙酮 合成 |
The Synthesis of 2,5-Dimethyl-3,4-Diacetylfuran and Its Derivatives |
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| Zhu Hongyou,Yuan Jin,He Hongping,Liu Fuchu.The Synthesis of 2,5-Dimethyl-3,4-Diacetylfuran and Its Derivatives[J].Yunnan Chemical Technology,1997(2):28-29. |
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| Authors: | Zhu Hongyou Yuan Jin He Hongping Liu Fuchu |
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| Abstract: | This paper reported the synthesis of 2,5-dimethyl-3,4 diacetylfuran (7) and 2,5-dimethyl-3,4-diethoxycarbonyl (8),which is given in TsOH/benene-ethy1 acetate system through Paal-Knorr cyclization of the electroxidative coupling products of acetoacetone (3) and ethyl acetylacetate (4), respectively. Then, (7) was reduced by NaBH 4/CH 3OH, providing the reductive product 2,5-dimethyl-3,4-bi(1-hydroxyethy1)furan (9). |
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| Keywords: | indirect electroxidition coupling reaction synthesis KI-NaI/acetone polysubstituted furan |
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