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谢氏丙酸杆菌发酵废液中生物抑菌物质的研究
引用本文:卢楠,朱文华.谢氏丙酸杆菌发酵废液中生物抑菌物质的研究[J].河北机电学院学报,2012(3):138-140,145.
作者姓名:卢楠  朱文华
作者单位:[1]河北化工医药职业技术学院制药工程系,河北石家庄050026 [2]石家庄科技信息职业学院医药化工系,河北石家庄050091
摘    要:对生产维生素B12的谢氏丙酸杆菌发酵废液中是否存在生物抑菌物质,其性质、抑菌作用大小及抗菌谱进行了研究。研究表明,谢氏丙酸杆菌的发酵液针对检验菌的抑菌效果明显优于化学防腐剂且抑菌谱较广,可以抑制一些革兰氏阳性菌、阴性菌及真菌,其中主要抑菌成分为等电点在2.0附近的蛋白类物质、丙酸氨、乙酸氨。

关 键 词:生物抑菌物质  发酵液  抑菌作用  抑菌谱

Study on biological antibacterial material in fermentation liquor of propionibacterium shermanii
Authors:LU Nan  ZHU Wen-hua
Affiliation:1. Department of Pharmaceutical Engineering, Hebei Chemical and Pharmaceutical Vocational Technology College, Shijiazhuang Hebei 050026,Chinas2. Department of Medicine and Chemical Industry, Science and Technology and Information College of Shijiazhuang, Shijiazhuang Hebei 050091 ,China)
Abstract:Whether there is biological antibacterial material in the fermentation liquor of propionibaeterium shermanii is stud- ied, so are the nature,the antimicrobial effect and the antibacterial range. The results are as follows: The fermentation liquor has distinct inhibitory effect and wide antibacterial range comparing with chemical preservatives. The inhibitory effect is mainly for Gram-negative, Gram-positive bacteria and mildew. The effective antibiotic composition has protein ammonium propionate and ammonium acetate, at the isoelectric point of 2.0.
Keywords:biological antibacterial material  fermentation liquor  antimierobial effect  antibacterial range
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