Comparison of Postprandial Oleic Acid, 9c,11t CLA and 10t,12c CLA Oxidation in Healthy Moderately Overweight Subjects |
| |
Authors: | Corinne Malpuech-Brugère Ronald P. Mensink Olivier Loreau Agnès Maret Claire E. Fernie Taous S. Lassel Jean Michel Chardigny Jean Louis Sébédio Bernard Beaufrère |
| |
Affiliation: | 1.UMR1019 Nutrition Humaine,INRA,Saint Genès Champanelle,France;2.Clermont Université, UFR Médecine, UMR 1019 Nutrition Humaine,Clermont-Ferrand,France;3.CRNH Auvergne,Clermont-Ferrand,France;4.Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht,Maastricht University,Maastricht,The Netherlands;5.Service de Marquage Moléculaire et de Chimie Bioorganique,CEA,Gif-sur-Yvette,France;6.Scottish Crop Research Institute,Dundee,Scotland, UK;7.Danone Research Center Daniel Carasso,Palaiseau,France;8.UMR 1019, Equipe du Métabolisme Lipidique et Energétique, Laboratoire de Nutrition Humaine,Clermont-Ferrand Cedex 1,France |
| |
Abstract: | Few studies report the individual effect of 9c,11t- and 10t,12c-CLA on human energy metabolism. We compared the postprandial oxidative metabolism of 9c,11t- and 10t,12c-CLA and oleic acid (9c-18:1) in 22 healthy moderately overweight volunteers. After 24 weeks supplementation with 9c,11t-, 10t,12c-CLA or 9c-18:1 (3 g/day), subjects consumed a single oral bolus of the appropriate [1-13C]-labeled fatty acid. 8 h post-dose, cumulative oxidation was similar for 9c-18:1 and 10t,12c (P = 0.66), but significantly higher for 9c,11t (P < 0.01). |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|