| KF/Al2O3催化反应精馏制备1-羟基-2-甲基-4-乙酰氧基-2-丁烯的研究 |
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| 引用本文： | 沈润溥,孔识卫,胡四平,陈春峰,张伯引,王再中.KF/Al2O3催化反应精馏制备1-羟基-2-甲基-4-乙酰氧基-2-丁烯的研究[J].江苏化工,2006,34(17):16-18. |
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| 作者姓名： | 沈润溥 孔识卫 胡四平 陈春峰 张伯引 王再中 |
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| 作者单位： | 1. 绍兴文理学院化学化工学院,浙江,绍兴,312000
2. 浙江医药股份有限公司维生素厂,浙江,新昌,312000 |
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| 摘 要： | 用KF/Al2O3催化1-甲酰氧基-2-甲基-4-乙酰氧基-2-丁烯进行酯交换反应制备1-羟基-2-甲基-4-乙酰氧基-2-丁烯,提高了反应选择性,并因采用反应精馏方式将反应时间缩短到5h,收率由77%提高到95%,后处理方便。
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| 关 键 词： | VA乙酸酯 1-羟基-2-甲基-4-乙酰氧基-2-丁烯 1-甲酰氧基-2-甲基-4-乙酰氧基-2-丁烯 酯交换反应 KF/Al2O3 反应精馏 |
| 文章编号： | 1002-1116(2006)17-0016-03 |
| 修稿时间： | 2006年4月21日 |
Catalytic Synthesis of 1-Hydroxy-2-methyl-4-acetyloxy-2-butene with KF/Al2O3 by Reaction-distillation |
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| SHEN Run-pu,KONG Shi-wei,HU Si-ping,CHEN Chun-feng,ZHANG Bo-yin,WANG Zai-zhong.Catalytic Synthesis of 1-Hydroxy-2-methyl-4-acetyloxy-2-butene with KF/Al2O3 by Reaction-distillation[J].Jiangsu Chemical Industry,2006,34(17):16-18. |
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| Authors: | SHEN Run-pu KONG Shi-wei HU Si-ping CHEN Chun-feng ZHANG Bo-yin WANG Zai-zhong |
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| Abstract: | 1-Hydroxy-2-methyl-4- acetyloxy-2- butene was prepared by ester exchange reaction catalyzed by KF/Al2O3 from 1-formyloxy-2-methyl-4- acetyloxy-2-butene,the reaction selectivity is enhanced. Moreover,reaction time is shortcut,yield is raised and the process is simplified by the adoption of reaction-distillation method,which has a great industrial value. This new method demonstrates significance to the synthesis of similar compound via ester exchange reaction. |
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| Keywords: | retinol acetate 1-hydroxy-2-methyl-4- acetyloxy-2-butene 1-formyloxy-2-methyl-4-acetyloxy-2-butene ester exchange reaction KF/Al2O3 reaction-distillation |
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