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| RADIOIMMUNOTOXICOLOGICAL EFFECT OF ENRICHED URANIUM ON CENTRAL AND PERIPHERAL IMMUNE CELLS AND THE PROTECTIVE ACTION OF IL－1 AND IL－2 | |
| 引用本文： | 朱寿彭,赖冠华,王六一. RADIOIMMUNOTOXICOLOGICAL EFFECT OF ENRICHED URANIUM ON CENTRAL AND PERIPHERAL IMMUNE CELLS AND THE PROTECTIVE ACTION OF IL－1 AND IL－2[J]. 核技术(英文版), 1994, 0(2) |
| 作者姓名： | 朱寿彭 赖冠华 王六一 |
| 作者单位： | Faculty of Radiological Medicine,Suzhou Medical College,Suzhou 215007,China |
| 摘 要： | ＲＡＤＩＯＩＭＭＵＮＯＴＯＸＩＣＯＬＯＧＩＣＡＬＥＦＦＥＣＴＯＦＥＮＲＩＣＨＥＤＵＲＡＮＩＵＭＯＮＣＥＮＴＲＡＬＡＮＤＰＥＲＩＰＨＥＲＡＬＩＭＭＵＮＥＣＥＬＬＳＡＮＤＴＨＥＰＲＯＴＥＣＴＩＶＥＡＣＴＩＯＮＯＦＩＬ－１ＡＮＤＩＬ－２￥ＺｈｕＳｈｏｕｐｅ... |
RADIOIMMUNOTOXICOLOGICAL EFFECT OF ENRICHED URANIUM ON CENTRAL AND PERIPHERAL IMMUNE CELLS AND THE PROTECTIVE ACTION OF IL-1 AND IL-2 |
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| Zhu Shoupeng, Lai Guanhua and Wang Liuyi. RADIOIMMUNOTOXICOLOGICAL EFFECT OF ENRICHED URANIUM ON CENTRAL AND PERIPHERAL IMMUNE CELLS AND THE PROTECTIVE ACTION OF IL-1 AND IL-2[J]. , 1994, 0(2) | |
| Authors: | Zhu Shoupeng Lai Guanhua Wang Liuyi |
| Abstract: | Accumulation of enriched 235U-UO2F2 in the body had injurious effects on theimmune function of central and peripheral immune cells. After an intravenousinjection of beaU--UO,F,, the spontaneous 'H--TdR incorporation in thymocytes andbone marrow cells decreased, with the thymocytes damaged more markedly. Theproliferation ability of spleen T and B lymphocytes were both inhibited, with Blymphocytes inhibited more severely. In spleen B lymphocytes the IL-- 1 production andIL--2 consumption were diminished. The inhibition of spleen B lymphocyteproliferation by "U-- UOZFZ was partially restored by adding exogenous IL-- 1 or IL--2to the cultured lymphocytes obtained from "U injected mice. |
| Keywords: | Enriched uranium Radioimmunotoxicological effect Interleukin-1 Interleukin-2 Immune cells Protective action |
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