Development of Diffusion-Thermal Methods for Preparing 67Cu and 124I for Radionuclide Therapy and Positron Emission Tomography |
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| Authors: | I. E. Alekseev V. V. Darmograi N. S. Marchenkov |
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| Affiliation: | (1) St. Petersburg State University, St. Petersburg, Russia;(2) Prometei Central Research Institute of Structural Materials, St. Petersburg, Russia;(3) Russian Research Centre Kurchatov Institute, Moscow, Russia |
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| Abstract: | Diffusion-thermal procedures for preparing 67Cu and 124I for radionuclide therapy and positron emission tomography are suggested. For these procedures, new cyclotron targets of metallic tantalum were developed, which, when exposed to high irradiation doses, ensure the absence of physicochemical interaction (diffusion, alloying) of materials being activated and final products with the support at high temperatures. The thermal, hydrodynamic, and strength characteristics of zinc and tellurium (elemental Te) cyclotron targets were evaluated. For commercial target assembly of the COSTIS system, the operation parameters of the process for preparing 124I from elemental tellurium using the derived beams of IBA Cyclone 18/9 or MGTs- 20 accelerators were determined. |
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