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3,5-二羟基苯腈的合成
引用本文:张万轩,黄巍,曹锰. 3,5-二羟基苯腈的合成[J]. 精细化工中间体, 2010, 40(4): 51-52
作者姓名:张万轩  黄巍  曹锰
作者单位:湖北大学,有机功能分子合成与应用教育部重点实验室,湖北,武汉,430062
摘    要:
以3,5-二羟基苯甲酸为原料,乙酸酐、氨水、二氯亚砜作为试剂,经4步反应合成了3,5-二羟基苯腈,总收率66%。

关 键 词:3,5-二羟基苯甲酸  3,5-二羟基苯腈  合成

Synthesis of 3,5-Dihydroxy Benzonitrile
ZHANG Wan-xuan,HUANG Wei,CAO Meng. Synthesis of 3,5-Dihydroxy Benzonitrile[J]. Fine Chemical Intermediates, 2010, 40(4): 51-52
Authors:ZHANG Wan-xuan  HUANG Wei  CAO Meng
Affiliation:(Key Laboratory for the Synthesis and Application of Organic Functional Molecules,Ministry of Education,Hubei University,Wuhan 430062,China)
Abstract:
3,5-Dihydroxy benzonitrile,a versatile intermediate for the synthesis of bioactive compounds,was synthesized in four steps in an overall yield of 66% starting from 3,5-dihydroxybenzoic acid.The other reagents used included acetic anhydride,ammonia and thionyl chloride.
Keywords:3  5-dihydroxybenzoic acid  3  5-dihydroxy benzonitrile  synthesis
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