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小球藻类金属硫蛋白抗紫外辐射的作用研究
引用本文:杨 红,黄晓淳,黄婧筠,彭爱红,黄志勇. 小球藻类金属硫蛋白抗紫外辐射的作用研究[J]. 日用化学工业, 2017, 47(1): 28-31
作者姓名:杨 红  黄晓淳  黄婧筠  彭爱红  黄志勇
作者单位:集美大学 食品与生物工程学院
基金项目:厦门市海洋经济发展专项(14GZP67NF31);集美大学创新团队基金资助项目(2010A007)
摘    要:建立了小鼠胚胎成纤维(NIH/3T3)细胞紫外辐射损伤的实验模型,考察小球藻类金属硫蛋白(Zn-MT-like)对NIH/3T3细胞紫外辐射的保护作用。结果表明,小球藻Zn-MT-like对NIH/3T3细胞的生长无抑制作用,且具有较强的抗紫外辐射能力。质量浓度为10 g/L的小球藻Zn-MT-like可显著减少NIH/3T3细胞空泡、降低细胞裂解的程度,可使经紫外辐射的NIH/3T3细胞保持较好的活性。

关 键 词:抗紫外辐射;小球藻;类金属硫蛋白;NIH/3T3细胞模型
收稿时间:2016-08-10

Protective effect of Zn-MT-like extracted from C. vulgaris for NIH/3T3 cells against ultraviolet irradiation
YANG Hong,HUANG Xiao-chun,HUANG Jing-yun,PENG Ai-hong and HUNG Zhi-yong. Protective effect of Zn-MT-like extracted from C. vulgaris for NIH/3T3 cells against ultraviolet irradiation[J]. China Surfactant Detergent & Cosmetics, 2017, 47(1): 28-31
Authors:YANG Hong  HUANG Xiao-chun  HUANG Jing-yun  PENG Ai-hong  HUNG Zhi-yong
Affiliation:College of Food and Biological Engineering, Jimei University
Abstract:A laboratory model for testing ultraviolet irradiation damage of fibroblast (NIH/3T3) of mouse embryo was established; and it was applied for examination of protective effect of Zine-binding metallothionein-like (Zn-MT-like) extracted from C. vulgaris for NIH/3T3 cells against ultraviolet irradiation. Results showed that the Zn-MT-like presents a strong protective effect for the NH/3T3 cells from irradiation damage. For example, the Zn-MT-like at mass concentration of 10 g/L can effectively reduce the NIH/3T3 cell cavity and cell fragmentation under the ultraviolet irradiation, and maintaining rather good cell activity.
Keywords:anti ultraviolet irradiation   C. vulgaris   Zn-MT-like   NIH/3T3 cells model
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