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| 一种新型的骨组织工程用支架材料的制备与性能表征 | |
| 引用本文： | 王德平,黄文旵,周萘,姚爱华,宁佳,刘欣. 一种新型的骨组织工程用支架材料的制备与性能表征[J]. 功能材料, 2007, 38(2): 302-304,307 |
| 作者姓名： | 王德平 黄文旵 周萘 姚爱华 宁佳 刘欣 |
| 作者单位： | 同济大学,材料科学与工程学院,上海,200092 |
| 基金项目： | 上海市重点基础研究项目 |
| 摘 要： | 以硼硅酸盐玻璃粉为原料,采用有机泡沫浸渍工艺,制备了高孔隙率的网眼多孔支架.应用XRD、SEM及ICP-AES等对硼酸盐生物玻璃粉末在生理模拟液中的降解性能、生物活性等进行了测试分析.结果表明,硼硅酸盐生物玻璃的降解性和生物活性与材料的组成配比有关,因此,可以通过调整玻璃的组成有效控制材料的降解性和表面形成的羟基磷灰石晶体的形态.硼硅酸盐生物活性玻璃作为硬组织工程支架材料的研究具有重要的意义和广泛的应用前景. |
| 关 键 词： | 支架材料 硼硅酸盐玻璃 生物活性玻璃 生物降解性 生物活性 |
| 文章编号： | 1001-9731（2007）02-0302-03 |
| 修稿时间： | 2006-08-302006-10-31 |
The peparation and characterization of novel scaffold materials for bone tissue engineering |
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| WANG De-ping,HUANG Wen-hai,ZHOU Nai,YAO Ai-hua,NING Jia,LIU Xin. The peparation and characterization of novel scaffold materials for bone tissue engineering[J]. Journal of Functional Materials, 2007, 38(2): 302-304,307 | |
| Authors: | WANG De-ping HUANG Wen-hai ZHOU Nai YAO Ai-hua NING Jia LIU Xin |
| Affiliation: | School of Materials Science and Engineering,Tongji University, Shanghai 200092,China |
| Abstract: | Three-dimensional(3D),highly porous scaffolds with interconnected pore morphologies similar to trabecular bone have been fabricated by polymer sponge method using melt-derived borosilicate glass powder.The biodegradation and bioactivity of borosilicate glass powder were investigated in vitro method combined with XRD,SEM and ICP-AES techniques.It indicated that there is a connection between the composition of materials and the biodegradation,as well as bioactivity.The degradation rate can be adjusted by the boron concentration in the bioglass.It indicated that borosilicate glass is a promising scaffolds biomaterial for bone tissue engineering. |
| Keywords: | scaffolds borosUlcate glass bioactive glass biodegradation bioactivity |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |