| 一步法合成3(5)-氨基吡唑 |
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| 引用本文： | 宫园园.一步法合成3(5)-氨基吡唑[J].山东化工,2011,40(1):31-33. |
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| 作者姓名： | 宫园园 |
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| 作者单位： | 青岛科技大学,化学与分子工程学院,山东,青岛,266042 |
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| 摘 要： | 3(5)-氨基吡唑是一个重要的农药医药有机合成中间体。比较了3(5)-氨基吡唑的各种合成方法,探索了一条以2-氯丙烯腈为原料,一步法合成3(5)-氨基吡唑的经济合理的路线,收率70%,含量99.4%。该工艺具有反应条件温和,易操作,溶剂易回收,成本低的特点。
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| 关 键 词： | 2-氯丙烯腈 水合肼 3(5)-氨基吡唑 一步法 |
One-step Synthesis of 3(5)-Amino-pyrazole |
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| GONG Yuan-yuan.One-step Synthesis of 3(5)-Amino-pyrazole[J].Shandong Chemical Industry,2011,40(1):31-33. |
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| Authors: | GONG Yuan-yuan |
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| Affiliation: | GONG Yuan - yuan( College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China) |
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| Abstract: | 3 （5） - amino pyrazole is an important synthetic organic intermediate, belongs to pesticide and medicine. Compared various synthesis methods of the 3 （5） - amino pyrazole, explored an economic and reasonable route （ one - step synthesis method）, which used 2 - chlorineaerylonitrile as raw materials to get 3（5） - amino pyrazole. Finally,the yield reached 70% and the content was 99.4%. This process has mild reaction condition, easy operation, solvent easily recycled, low cost characteristic. |
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| Keywords: | 2 - chloroacrylonitrile hydrazine hydrate 3 （5） - amino - pyrazole one - step method |
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