Smooth-pursuit eye movements: A comparison of two measurement techniques for studying schizophrenia.

Conducted simultaneous recording of smooth-pursuit eye movements by EOG and infrared reflection techniques with 5 psychiatric patients (1 with psychotic depression, 1 with organic brain syndrome, and 3 with schizophrenia) and 5 normal controls. Results show good correspondence between the 2 methods. The parameter of pursuit arrests, previously used to quantify smooth-pursuit performance, was not well correlated in the 2 methods. The natural logarithm of the signal/noise ratio obtained from harmonic regression of digitized and standardized eye movement data provides a valid quantitative assessment of smooth pursuit and suggests that such scoring of EOG records is effective and generally free of artifacts. (PsycINFO Database Record (c) 2010 APA, all rights reserved)