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A review of the antioxidant potential of medicinal plant species
Authors:Duduku Krishnaiah  Rosalam Sarbatly  Rajesh Nithyanandam
Affiliation:Phytochemical Laboratory, Department of Chemical Engineering, School of Engineering and Information Technology, Universiti Malaysia Sabah, 88999 Kota Kinabalu, Malaysia
Abstract:Some researchers suggest that two-thirds of the world's plant species have medicinal value; in particular, many medicinal plants have great antioxidant potential. Antioxidants reduce the oxidative stress in cells and are therefore useful in the treatment of many human diseases, including cancer, cardiovascular diseases and inflammatory diseases. This paper reviews the antioxidant potential of extracts from the stems, roots, bark, leaves, fruits and seeds of several important medicinal species. Synthetic antioxidants such as butylated hydroxytoluene (BHT) and butylated hydroxylanisole (BHA) are currently used as food additives, and many plant species have similar antioxidant potentials as these synthetics. These species include Diospyros abyssinica, Pistacia lentiscus, Geranium sanguineum L., Sargentodoxa cuneata Rehd. Et Wils, Polyalthia cerasoides (Roxb.) Bedd, Crataeva nurvala Buch-Ham., Acacia auriculiformis A. Cunn, Teucrium polium L., Dracocephalum moldavica L., Urtica dioica L., Ficus microcarpa L. fil., Bidens pilosa Linn. Radiata, Leea indica, the Lamiaceae species, Uncaria tomentosa (Willd.) DC, Salvia officinalis L., Momordica Charantia L., Rheum ribes L., and Pelargonium endlicherianum. The literature reveals that these natural antioxidants represent a potentially side effect-free alternative to synthetic antioxidants in the food processing industry and for use in preventive medicine.
Keywords:Abbreviations: ABTS, 2,2&prime  -azinobis(3-ethylbenzthiazoline-6-sulphonic acid)   ATC, ammonium thiocyanate   BHA, butylated hydroxylanisole   BHT, butylated hydroxytoluene   BR, Briggs Rauscher   DAD, diode array detector   DPPH, 1,1-diphenyl-2-picrylhydrazine   FRAP, ferric reducing antioxidant power   FTC, ferric thiocyanate   FTC, Folin-Ciocalteau   GA, gallic acid   GAE, gallic acid equivalents   GPx, glutathione peroxidase   HPLC, high performance liquid chromatography   LPO, lipid peroxidation   NBT, nitro blue tetrazolium   ORAC, oxygen radical absorbance capacity   PCL, luminol-photochemiluminescence   PEs, pyrocatechol equivalents   PG, propyl gallate   PMS-NADH, phenazine methosulfate&ndash  nicotinamide adenine dinucleotide-reduced   QEs, quercetin equivalents   Re eq., resorcinol equivalents   ROS, reactive oxygen species   SOD, superoxide dismutase   TBA, thiobarbituric acid   TEAC, trolox equivalent antioxidant capacity   TFA, total flavonoids   TFO, total flavonols   TP, total phenols   TPC, total phenolic content   TRAP, total radical-trapping antioxidant potential   WHO, World Health Organization
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