A review of the antioxidant potential of medicinal plant species |
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Authors: | Duduku Krishnaiah Rosalam Sarbatly Rajesh Nithyanandam |
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Affiliation: | Phytochemical Laboratory, Department of Chemical Engineering, School of Engineering and Information Technology, Universiti Malaysia Sabah, 88999 Kota Kinabalu, Malaysia |
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Abstract: | Some researchers suggest that two-thirds of the world's plant species have medicinal value; in particular, many medicinal plants have great antioxidant potential. Antioxidants reduce the oxidative stress in cells and are therefore useful in the treatment of many human diseases, including cancer, cardiovascular diseases and inflammatory diseases. This paper reviews the antioxidant potential of extracts from the stems, roots, bark, leaves, fruits and seeds of several important medicinal species. Synthetic antioxidants such as butylated hydroxytoluene (BHT) and butylated hydroxylanisole (BHA) are currently used as food additives, and many plant species have similar antioxidant potentials as these synthetics. These species include Diospyros abyssinica, Pistacia lentiscus, Geranium sanguineum L., Sargentodoxa cuneata Rehd. Et Wils, Polyalthia cerasoides (Roxb.) Bedd, Crataeva nurvala Buch-Ham., Acacia auriculiformis A. Cunn, Teucrium polium L., Dracocephalum moldavica L., Urtica dioica L., Ficus microcarpa L. fil., Bidens pilosa Linn. Radiata, Leea indica, the Lamiaceae species, Uncaria tomentosa (Willd.) DC, Salvia officinalis L., Momordica Charantia L., Rheum ribes L., and Pelargonium endlicherianum. The literature reveals that these natural antioxidants represent a potentially side effect-free alternative to synthetic antioxidants in the food processing industry and for use in preventive medicine. |
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Keywords: | Abbreviations: ABTS, 2,2&prime -azinobis(3-ethylbenzthiazoline-6-sulphonic acid) ATC, ammonium thiocyanate BHA, butylated hydroxylanisole BHT, butylated hydroxytoluene BR, Briggs Rauscher DAD, diode array detector DPPH, 1,1-diphenyl-2-picrylhydrazine FRAP, ferric reducing antioxidant power FTC, ferric thiocyanate FTC, Folin-Ciocalteau GA, gallic acid GAE, gallic acid equivalents GPx, glutathione peroxidase HPLC, high performance liquid chromatography LPO, lipid peroxidation NBT, nitro blue tetrazolium ORAC, oxygen radical absorbance capacity PCL, luminol-photochemiluminescence PEs, pyrocatechol equivalents PG, propyl gallate PMS-NADH, phenazine methosulfate&ndash nicotinamide adenine dinucleotide-reduced QEs, quercetin equivalents Re eq., resorcinol equivalents ROS, reactive oxygen species SOD, superoxide dismutase TBA, thiobarbituric acid TEAC, trolox equivalent antioxidant capacity TFA, total flavonoids TFO, total flavonols TP, total phenols TPC, total phenolic content TRAP, total radical-trapping antioxidant potential WHO, World Health Organization |
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