The transcriptional program in the response of human fibroblasts to serum |
| |
| Authors: | VR Iyer MB Eisen DT Ross G Schuler T Moore JC Lee JM Trent LM Staudt J Hudson MS Boguski D Lashkari D Shalon D Botstein PO Brown |
| |
| Affiliation: | Department of Biochemistry, Stanford University School of Medicine, Stanford CA 94305, USA. |
| |
| Abstract: | The temporal program of gene expression during a model physiological response of human cells, the response of fibroblasts to serum, was explored with a complementary DNA microarray representing about 8600 different human genes. Genes could be clustered into groups on the basis of their temporal patterns of expression in this program. Many features of the transcriptional program appeared to be related to the physiology of wound repair, suggesting that fibroblasts play a larger and richer role in this complex multicellular response than had previously been appreciated. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
