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左舒必利片的溶出度测定
引用本文:王乐. 左舒必利片的溶出度测定[J]. 河北化工, 2011, 34(2): 28-29
作者姓名:王乐
作者单位:河北化工医药职业技术学院,河北,石家庄,050026
摘    要:建立了左舒必利片溶出度的测定方法。以0.1 mol/L盐酸溶液为溶出介质,采用桨法(50 r/min)20 min取样,使用紫外-可见分光光度法测定溶出度,检测波长为291 nm,考察了溶出曲线,样品溶出度〉90%,该方法可用于左舒必利片的溶出度测定。

关 键 词:左舒必利片  溶出度  紫外-可见分光光度法  测定

Determination of Dissolution Levosulpiride Tablets
WANG Le. Determination of Dissolution Levosulpiride Tablets[J]. Hebei Chemical Engineering and Industry, 2011, 34(2): 28-29
Authors:WANG Le
Affiliation:WANG Le(Hebei Vocational Technology College of Chemistry & Medicament,Shijiazhuang 050026,China)
Abstract:To establish a method to determine the dissolution of the levosulpiride tablets.The oar method(50 r/min) was adopted with dissolution medium of 0.1 mol/L hydrochloride acid and sampling after 20 min.The dissolution was determined by UV and the detection wavelength was set at 291 nm.The dissolution curve was investigated.Three batches of samples’ dissolution was investigated,and the results were all above 90 %.This method can be used to investigate and control the quality of the levosulpiride tablets.
Keywords:levosulpiride tablets  dissolution  UV  determination
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