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代谢热整合法无创血糖检测技术研究
引用本文:唐飞,王晓浩,王东生,李俊峰,徐效文.代谢热整合法无创血糖检测技术研究[J].仪器仪表学报,2007,28(10):1857-1860.
作者姓名:唐飞  王晓浩  王东生  李俊峰  徐效文
作者单位:清华大学精密仪器与机械学系,精密测试技术与仪器国家重点实验室,北京,100084
摘    要:介绍了一种新的基于代谢热整合法的无创血糖检测技术。采用温度传感器、红外传感器、湿度传感器和光学测量装置,通过测量人体代谢产生的热量、血液流速、血氧饱和度,利用人体代谢产生的热量是血糖浓度、供氧量的函数,可以推算出血糖浓度。介绍了系统的组成、数据处理方法及可能造成误差的因素。用所研制的检测系统进行了临床实验,得到的血糖值与用大型生化分析仪测得的血糖值的相关系数达到0.856。实验证明,代谢热整合法无创血糖检测技术是可行的。

关 键 词:血糖  无创检测  代谢热整合法
修稿时间:2006-11

Research on noninvasive glucose measurement based on metabolic heat conformation method
Tang Fei,Wang Xiaohao,Wang Dongsheng,Li Junfeng,Xu Xiaowen.Research on noninvasive glucose measurement based on metabolic heat conformation method[J].Chinese Journal of Scientific Instrument,2007,28(10):1857-1860.
Authors:Tang Fei  Wang Xiaohao  Wang Dongsheng  Li Junfeng  Xu Xiaowen
Affiliation:State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instruments and Mechanology, Tsinghna University, Beijing 100084, China
Abstract:A noninvasive glucose measurement system is proposed using metabolic heat conformation method, which is based on the discovery that the heat quantity dissipated in metabolism is the function of glucose level and the quantity of oxygen supply. Temperature sensors, infrared sensors, moisture sensors and optical measurement device are applied to get the glucose level by measuring heat dissipation, blood flow rate of the local tissue and local blood oxygen level. The measurement system composition and data processing method as well as the possible sources of the measurement errors are introduced. In clinical test, comparing with the test results obtained from large automatic biochemical analyzer, the correlation coefficient of the system test results equals to 0.856, which proves that the proposed method is feasible.
Keywords:glucose  noninvasive measurement  metabolic heat conformation method
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