| 1，3一二氨基胍盐酸盐的高效液相色谱分析 |
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| 引用本文： | 申克静,夏佳美,贾爱铨,张千峰.1，3一二氨基胍盐酸盐的高效液相色谱分析[J].化学工业与工程技术,2014,35(4):74-76. |
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| 作者姓名： | 申克静 夏佳美 贾爱铨 张千峰 |
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| 作者单位： | 安徽工业大学现代分析测试中心,安徽马鞍山,243002 |
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| 摘 要： | 提出用高效液相色谱法测定1，3-二氨基胍盐酸盐的含量，选用甲醇与乙酸铵缓冲盐体积比75：25为流动相，c8色谱柱，检测波长314nm。试验结果表明：测试结果的相对标准偏差小于2．03％；回收率在97．8％～100．2％；1，3-二氨基胍盐酸盐和三氨基胍盐酸盐得到较好的分离。该法操作简单、实用且定量分析结果准确稳定。
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| 关 键 词： | 1 3一二氨基胍盐酸盐 三氨基胍盐酸盐 高效液相色谱 |
Determination of 1,3-diaminoguanidine monohydrochloride by HPLC |
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| SHEN Kejing,XIA Jiamei,JIA Aiquan,ZHANG Qianfeng.Determination of 1,3-diaminoguanidine monohydrochloride by HPLC[J].Journal of Chemical Industry & Engineering,2014,35(4):74-76. |
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| Authors: | SHEN Kejing XIA Jiamei JIA Aiquan ZHANG Qianfeng |
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| Affiliation: | SHEN Kejing;XIA Jiamei;JIA Aiquan;ZHANG Qianfeng;Institute of Molecular Engineering and Applied Chemistry, Anhui University of Technology; |
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| Abstract: | The content of 1,3-diaminoguanidine monohydroehloride is determined by HPLC using chromatographic column packed with C8. The mobile phase is methanol and ammonium acetate buffer salt with volume ratio of 75 ： 25. The detection wave length is at 254 nm. The results show that the standard deviation is less than 2. 03%, and the recovery is between 98.0%～ 100. 1%. 1,3-Diamin- oguanidine monohydrochloride is effectively separated from triaminoguanidine monohydroehloride. This method has advantages of simple operation, practical and accuracy. |
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| Keywords: | 1 3-diaminoguanidine monohydrochloride triaminoguanidine monohydrochloride HPLC |
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