Methods of measuring susceptibility of anaerobic bacteria to trovafloxacin, including quality control parameters |
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Authors: | AL Barry PC Fuchs C Thornsberry JC McLaughlin SG Jenkins DJ Hardy SD Allen |
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Affiliation: | Clinical Microbiology Institute, Tualatin, Oregon 97062, USA. |
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Abstract: | Three methods approved by the National Committee for Clinical Laboratory Standards for testing the susceptibility of anaerobic bacteria were used to evaluate the fluoroquinolone, trovafloxacin. The methods gave essentially comparable results with 126 anaerobes and with three quality control strains. A collaborative study defined the quality control range for trovafloxacin MICs. Trovafloxacin had good in vitro activity against the more common anaerobes (MIC 90 < = or 2.0 micrograms/ml). |
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