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VC二步发酵高糖流加工艺的研究
引用本文:张亚军,梁丙辰,李海涛.VC二步发酵高糖流加工艺的研究[J].河北化工,2006,29(8):37-39.
作者姓名:张亚军  梁丙辰  李海涛
作者单位:1. 华北制药集团维尔康公司,河北,石家庄,050031
2. 河北省化学工业研究院,河北,石家庄,050031
摘    要:利用从生产中选育得到的耐高糖菌株,通过在线的检测数据,应用改进的高浓度山梨糖流加控制工艺,考察了初始山梨糖浓度、底物浓度、流加阶段pH等对维生素C二步发酵的影响,确定了适宜的控制工艺,提高了发酵水平及设备利用率.

关 键 词:维生素C  二步发酵  山梨糖  流加
文章编号:1003-5095(2006)08-0037-03
收稿时间:2006-05-26
修稿时间:2006年5月26日

Studies on a Fed-batch Technology of High Concentration L-Sorbose in VC Two-step Fermentation
ZHANG Ya-jun,LIANG Bing-chen,LI Hai-tao.Studies on a Fed-batch Technology of High Concentration L-Sorbose in VC Two-step Fermentation[J].Hebei Chemical Engineering and Industry,2006,29(8):37-39.
Authors:ZHANG Ya-jun  LIANG Bing-chen  LI Hai-tao
Affiliation:1. NCPC Welcome Co.,Ltd, Shijiazhuang 050031, China;2. Hebei chemical Engineering and Industry Research Institute, Shijiazhuang 050031,China
Abstract:Using a strain which be able to endured high concentration L-sorbose selected form the process of two-step VC fermentation, based on the data were on-line measured, and the improved control technology of High Concentration L-sorbose Fed-batch fermentation, we studied the effects of beginning concentration of L-sorbose ? substrate concentration and pH etc. on VC two-step fermentation. A control technology which was used to control fed-batch fermentation process of L-sorbose was obtained, and the level of fermentation and the rates of equipment were also improved.
Keywords:Vitamin C  two-step fermentation  L-sorbose  fed-batch
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