| 贫铀对啮齿类动物和人类生殖毒性研究进展 |
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| 引用本文： | 潘泽轩,尹晶晶,高洁,刘欢,李建国.贫铀对啮齿类动物和人类生殖毒性研究进展[J].辐射防护通讯,2020,40(1):38-42. |
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| 作者姓名： | 潘泽轩 尹晶晶 高洁 刘欢 李建国 |
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| 作者单位： | 中国辐射防护研究院放射医学与环境医学研究所;药物毒理与放射损伤药物山西省重点实验室,太原,030006 |
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| 摘 要： | 贫铀广泛应用,以多种形态存在于自然界中,其潜在的毒性威胁不容忽视。本文介绍了贫铀对啮齿类动物和人类生殖毒性的研究进展,主要包括对生殖器官损伤的严重程度、发展趋势、遗传损伤、作用方式、相关机制和研究方法等。研究表明,贫铀暴露在多个层面损伤啮齿类动物和人的生殖和遗传功能。
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| 关 键 词： | 贫铀 生殖系统 毒性研究 |
| 收稿时间： | 2020-01-20 |
Advances in Studies on Reproductive Toxicity of Depleted Uranium to Rodents and Humans |
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| Pan Zexuan,Yin Jingjing,Gao Jie,Liu Huan,Li Jianguo.Advances in Studies on Reproductive Toxicity of Depleted Uranium to Rodents and Humans[J].Radiation Protection Bulletin,2020,40(1):38-42. |
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| Authors: | Pan Zexuan Yin Jingjing Gao Jie Liu Huan Li Jianguo |
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| Affiliation: | China Institute for Radiation Protection, Key Laboratory of Drug Toxicology and Drug for Radiation Injury, Taiyuan, Shanxi, 030006 |
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| Abstract: | The research progress of the reproductive toxicity of depleted uranium to rodents and humans, is reviewed, including the severity of reproductive organ damage, the development trend, the genetic damage, action modes, related mechanisms and research methods. Studies have shown that depleted uranium exposure damages the reproductive and genetic functions of rodents and humans at multiple levels. |
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| Keywords: | Depleted uranium Reproductive system Toxicity studies |
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