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| 低能离子注入对脱氧胸苷的辐照损伤 | |
| 引用本文： | 邵春林 孙洪奎. 低能离子注入对脱氧胸苷的辐照损伤[J]. 核技术, 1996, 19(8): 484-487 |
| 作者姓名： | 邵春林 孙洪奎 |
| 作者单位： | 中国科学院等离子体物理研究所 |
| 摘 要： | 用紫外分光光度法测定了脱氧胸苷（ｄＴＲ）在２０ｋｅＶ Ｎ＾＋离子束辐照下残余活性Ｓ和碱基Ｔ释放量的剂量效应。发现Ｓ与样品的质量有关，且受损ｄＴＲ分子中约有５０％可产生碱基Ｔ。而强碱、强酸的后处理使这一比例显著下降，平均分别只有２３％和４１％，与γ辐射时的情况相反。 |
| 关 键 词： | 离子束 脱氧胸苷 辐照损伤 |
Irradiation-induced damage of thymidine by low energy ion implantation |
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| Shao Chunlin, Sun Hongkui, Yu Zengliang. Irradiation-induced damage of thymidine by low energy ion implantation[J]. Nuclear Techniques, 1996, 19(8): 484-487 | |
| Authors: | Shao Chunlin Sun Hongkui Yu Zengliang |
| Abstract: | With UV spectrophotometry, the dose effectS of residual activity S of thymidine irradiated by 20keV N+ ion beam and of based T released from the irradiated thymidine were studied. It was found that S was related to the irradiated sample's weight, and that about 50% of the damaged dTR molecules was able to produce based T. The post-treatment of strong alkali or strong acid made this proportion be reduced to 23% and 41% respectively, which showed a tendency contrary to that tinder gamma-ray irradiation. |
| Keywords: | Ion beam Thymidine Irradiation damage |
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