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A Tandem Chemoenzymatic Methylation by S‐Adenosyl‐L‐methionine
Authors:Joseph M. Lipson  Marie Thomsen  Prof. Bradley S. Moore  Dr. Rasmus P. Clausen  Dr. James J. La Clair  Prof. Michael D. Burkart
Affiliation:1. Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093‐0358 (USA);2. Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen (Denmark);3. Center for Marine Biotechnology and Biomedicine Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92097‐0204 (USA);4. The Skaggs School of Pharmacy and Pharmaceutical Science, University of California, San Diego, La Jolla, CA 92097‐0657 (USA)
Abstract:
Keywords:alkylation  chemoenzymatic synthesis  DNA methylation  methyltransferase  natural products
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