|
|||||
|
|
Inside Cover: Monitoring Binding of HIV‐1 Capsid Assembly Inhibitors Using 19F Ligand‐and 15N Protein‐Based NMR and X‐ray Crystallography: Early Hit Validation of a Benzodiazepine Series (ChemMedChem 3/2013) |
|
| Authors: | Dr. Nathalie Goudreau René Coulombe Dr. Anne‐Marie Faucher Chantal Grand‐Maître Jean‐Eric Lacoste Dr. Christopher T. Lemke Eric Malenfant Yves Bousquet Dr. Lee Fader Dr. Bruno Simoneau Jean‐François Mercier Steve Titolo Dr. Stephen W. Mason |
| Affiliation: | 1. Dept. of Chemistry and Biological Sciences, Research & Development, Boehringer Ingelheim (Canada) Ltd, 2100 Cunard Street, Laval, Québec, H7S 2G5 (Canada);2. Department of Chemistry, University of Montreal, C.P. 6128, succursale Centre‐ville, Montreal, Québec, H3C 3J7 (Canada);3. AL‐G Technologies Inc. 201 Mgr. Bourget, Lévis, Québec, G6V 9V6 (Canada);4. Virology, Bristol‐Myers Squibb, 5 Research Parkway, Wallingford, CT 06492 (USA) |
| Abstract: | |
| Keywords: | binding studies fluorine HIV‐1 capsids NMR spectroscopy X‐ray crystallography |