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The Cleavage Domain of the Amyloid Precursor Protein Transmembrane Helix Does Not Exhibit Above‐Average Backbone Dynamics
Authors:Oxana Pester  Alexander Götz  Prof Dr Gerd Multhaup  Dr Christina Scharnagl  Prof Dr Dieter Langosch
Affiliation:1. Lehrstuhl Chemie der Biopolymere, Technische Universit?t München and Munich Center For Integrated Protein Science (CIPSM), Weihenstephaner Berg 3, 85354 Freising (Germany);2. Current address: Roche Diagnostics GmbH, Nonnenwald 2, 82377 Penzberg (Germany);3. Department of Pharmacology and Therapeutics, McGill University, 3655 Promenade Sir‐William‐Osler, Montréal, Québec H3G 1Y6 (Canada);4. Fakult?t für Physik E14, Technische Universit?t München, Maximus‐von‐Imhof‐Forum 4, 85354 Freising (Germany)
Abstract:
Keywords:Alzheimer's disease  amide exchange  amyloid precursor proteins  membrane proteins  molecular dynamics  transmembrane domains
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