| Abstract: | Intraduodenal pHgraphy was used in experiments on thyroidine fed dogs with duodenal fistulas to study the time course of pH modulations without regard for, and during digestion. A decrease in the duodenal pH and occurrence of pH-waves on an empty stomach were recorded. After feeding the animals pH-waves disappeared and then recurred. They were arrhythmic in nature and unsteady in amplitude. The changes in the duodenal pH seen after thyroidine intake might be related to the processes of continuous acid output in the stomach induced by thyroid hormones and rapid evacuation of the acidic contents from the stomach to the duodenum. |
