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Preliminary Results for the Inhibition of Pancreatic Cancer Cells by Organotin Polymers |
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| Authors: | Michael R. Roner Kimberly R. Shahi Girish Barot Amitabh Battin Charles E. Carraher Jr. |
| Affiliation: | (1) Department of Biology, University of Texas Arlington, Arlington, TX 76010, USA;(2) Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL 33431, USA;(3) Florida Center for Environmental Studies, Palm Beach Gardens, FL 33410, USA |
| Abstract: | Pancreatic cancer kills nearly all patients within 3–6 months after detection. There is no effective chemotherapy for it. We have found a number of organotin polymers that are effective at inhibiting pancreatic cancer cell lines with Chemotherapeutic Index values greater than two with some to values of 50. |
| Keywords: | Pancreatic cancer Organotin polymers Pancreatic cancer chemotherapy Organotin polyethers Soluble organotin polyethers Organotin polyamines |
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