| 沙棘口服液中5-羟色胺的电化学检测 |
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| 引用本文： | 任旺,李敏娇,张英.沙棘口服液中5-羟色胺的电化学检测[J].化学试剂,2012(2):137-139. |
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| 作者姓名： | 任旺 李敏娇 张英 |
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| 作者单位： | 四川理工学院化学与制药工程学院 |
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| 基金项目： | 四川省教育厅基金资助项目(10ZB102);四川理工学院科技资助项目(2009xjky1001) |
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| 摘 要： | 采用电化学沉积法制备咖啡酸膜修饰电极,研究了5-羟色胺(5-HT)在该修饰电极上的电化学行为。结果表明,高浓度的抗坏血酸(AA)和肾上腺素(EP)共存不干扰5-HT的检测,5-HT在0.41 V和-0.12 V出现一对灵敏的氧化还原峰,其氧化峰电流与浓度在2.0×10-6～6.0×10-5mol/L范围内呈良好的线性关系,检测下限为8.0×10-7mol/L。该修饰电极制备简单,可准确检测神兴沙棘欣之安口服液中5-HT的含量。
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| 关 键 词： | 修饰电极 5-羟色胺 咖啡酸 |
Electrochemical determination of serotonin in oral liquid of fructus hippophae |
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| REN Wang,LI Min-jiao,ZHANG Ying.Electrochemical determination of serotonin in oral liquid of fructus hippophae[J].Chemical Reagents,2012(2):137-139. |
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| Authors: | REN Wang LI Min-jiao ZHANG Ying |
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| Affiliation: | (College of Chemical & Pharmaceutical Engineering,Sichuan University of Science & Engineering,Zigong 643000,China) |
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| Abstract: | Caffeic acid-modified electrode was constructed by potentiostatic technique.The electrochemical behavior of serotonin(5-HT) at modified electrode has been investigated by cyclic voltammetry(CV).The proposed electrode exhibits a promotion effect on the oxidation of 5-HT,and the interferences of ascorbic acid and epinephrine for determination of 5-HT have been investigated.The oxidative peak current obtained(ipa) is linearly dependent on the 5-HT concentrations in the range of 2.0×10-6~6.0×10-5 mol/L with the detection limit of 8.0×10-7 mol/L.This sensor was further applied for the determination of 5-HT in Chinese traditional drug Oral Liquid of Fructus Hippophae. |
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| Keywords: | modified electrode serotonin caffeic acid |
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