| 14.8 MeV单能中子所致淋巴细胞微核的剂量-效应关系 |
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| 引用本文： | 刘建功,段志凯,张淑贤,郭万龙. 14.8 MeV单能中子所致淋巴细胞微核的剂量-效应关系[J]. 辐射防护通讯, 2009, 29(4): 22-24 |
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| 作者姓名： | 刘建功 段志凯 张淑贤 郭万龙 |
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| 作者单位： | 中国辐射防护研究院,太原,030006 |
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| 摘 要： | 采用14.8 MeV单能中子对3名健康成人外周血进行照射,照射剂量分别为0.0、0.1、0.3、0.6、1.0、2.0、3.0、4.0 Gy,观察双核CB细胞微核,建立本实验室CB微核法的微核细胞率和微核率与受照剂量的剂量-效应关系。微核细胞率与中子剂量的回归方程为Y=14.8681＋43.3973D（r2=0.976）,Y=3.3758＋73.4099D-7.9360D2（r2=0.986）,Y=69.8514D0.6735（r2=0.986）;微核率与中子剂量的回归方程为Y=13.9096＋55.9122D（r2=0.986）,Y=2.6949＋85.1997D-7.7442D2（r2=0.991）,Y=81.5022D0.7367（r2=0.990）。结果表明,人体外周血CB细胞微核细胞率和微核率与14.8 MeV单能中子照射剂量存在良好的二次多项式和幂函数关系。
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| 关 键 词： | CB微核法 淋巴细胞 剂量-效应 中子 |
Research on Common Biological Dose Estimation Method of Monoenerge Neutron |
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| Liu Jiangong,Duan Zhikai,Zhang Shuxian,Guo Wanlong. Research on Common Biological Dose Estimation Method of Monoenerge Neutron[J]. Radiation Protection Bulletin, 2009, 29(4): 22-24 |
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| Authors: | Liu Jiangong Duan Zhikai Zhang Shuxian Guo Wanlong |
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| Affiliation: | Liu Jiangong Duan Zhikai Zhang Shuxian Guo Wanlong(China Institute for Radiation Protection,Taiyuan,030006) |
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| Abstract: | 14.8 MeV monoenergy neutron is used to irradiate peripheral blood of 3 healthy adults.Radiation dose is 0.0,0.1,0.3,0.6,1.0,2.0,3.0,and 4.0 Gy,respectively.Result indicates that there are good linear relations between rate of CB micronuclus and 14.8 MeV monoenergy neutron.Micronucleated cell regression equation is Y=14.8681+43.3973D(r2=0.976),Y=3.3758+73.4099D-7.9360D2(r2=0.989),Y=69.8514D(0.6735)(r2=0.986);and Monoenrgy neutron regression equation is Y=13.9096+55.9122D(r2=0.986),Y=2.6949+85.1997D-7.7442D2(... |
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| Keywords: | Micronucleated binucleated lymphocyte Micronuclear rates Dose-effect relation Neutron |
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